CD132, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD132, Human |
| Clone | REA313 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD132 Antibody, anti-human, PE, REAfinity™. Clone REA313 recognizes the human CD132 antigen, a 65-70 kDa single-pass type I membrane protein also known as common γ chain, which is shared by the IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 receptors. CD132 is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. The most common form of severe combined immune deficiency in humans, with lack of circulating T cells, a normal or increased number of B lymphocytes, and an X-linked pattern of inheritance (XSCID) has been shown to be due to defects of the CD132 gene. | Additional information: Clone REA313 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL2RG, CIDX, IL-2RG, IMD4, p64, SCIDX, SCIDX1 |
| Gene, Accession # | Gene ID: 3561 |
| Catalog # | 130-125-107 |
| Price | $114 |
| Order / More Info | CD132, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ramsey, C. et al. (2008) The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. J Immunol 180 (8): 5320-5326. | Russell, S. M. et al. (1993) Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science 262 (5141): 1880-1883. | Takesita, T. et al. (1992) Cloning of the gamma chain of the human IL-2 receptor. Science 257 (5068): 379-382. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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