CD366 (TIM-3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD366 (TIM-3), Human
CloneREAL226
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatallophycocyanin (APC) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD366 (TIM-3) Antibody, anti-human, APC, REAlease®. Clone REAL226 is an antibody fragment derived from the full CD366 (TIM-3) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL226 recognizes the human CD366 antigen, a single-pass type I membrane protein which is also known as T cell immunoglobulin and mucin domain containing protein-3 (TIM-3) or Hepatitis A virus cellular receptor 2 (HAVcr-2). CD366 is expressed on activated T cells, especially T?1 cells, monocytes, macrophages, and dendritic cells. It is an activation-induced inhibitory molecule involved in tolerance and shown to induce T cell exhaustion in chronic viral infection and cancers. CD366 has been proposed to inhibit T?1-mediated immune responses and regulates T?1 and T?17 cytokine secretion. The interaction of CD366 and its ligand galectin-9 induces apoptosis of T?1 cells. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
Immunogenn/a
Other NamesHAVcr-2, TIMD-3
Gene, Accession #n/a
Catalog #130-125-775
Price$164
Order / More InfoCD366 (TIM-3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific Referencesn/a
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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