IL-13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | IL-13, Human |
| Clone | REA1011 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | Vio B515 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-13 Antibody, anti-human, Vio® B515, REAfinity™. Clone REA1011 recognizes the interleukin-13 (IL-13), which is produced primarily by activated T?2 cells, but also by mast cells, natural killer (NK) cells, and dendritic cells (DCs). IL-13 exerts anti-inflammatory effects on monocytes and macrophages. Furthermore, it inhibits the expression of pro-inflammatory cytokines, such as IL-1β, TNF-α, IL-6, and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in an increased production of IgE. IL-13, in contrast to IL-4, fails to induce T?2 cell differentiation, one of the hallmarks of the allergic response. | Additional Information: Clone REA1011 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Interleukin-13 |
| Gene, Accession # | Gene ID: 3596 |
| Catalog # | 130-130-563 |
| Price | $382 |
| Order / More Info | IL-13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Minty, A. et al. (1993) Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 362 (6417): 248-250. | Wynn, T. (2003) IL-13 effector functions. Annu. Rev. Immunol. 21: 425-456. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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