CD252 (OX40L), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD252 (OX40L), Mouse |
| Clone | REA960 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD252 (OX40L) Antibody, anti-mouse, PE-Vio® 615, REAfinity™. Clone REA960 recognizes the mouse CD252 antigen, also known as OX40L, a ligand of the OX40 receptor belonging to the TNF superfamily. Expression of CD252 can be induced on B cells, dendritic cells, macrophages, mast cells, NK cells, endothelial cells, and smooth muscle cells. Expression of the cognate receptor OX40, is found on activated CD4 cells, CD8 cells, regulatory T cells, NKT cells, NK cells, and neutrophils, but the function of OX40 signaling is extensively studied only in T cells. CD252-OX40 interaction promotes the proliferation and surival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells (nTreg) and inhibits the generation of inducible Treg cells. | Additional information: Clone REA960 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | OX40L, TNFSF4, Ath-1, Ath1, CD134L, Txgp1, Txgp1l, gp34 |
| Gene, Accession # | Gene ID: 22164 |
| Catalog # | 130-116-075 |
| Price | $156 |
| Order / More Info | CD252 (OX40L), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J Immunol 162 (12): 7058-7066. | Croft, M. et al. (2009) The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol. Rev. 229 (1): 173-191. | Ishii, N. et al. (2010) OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology. Adv. Immunol. 105: 63-98. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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