CD8a, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD8a, Mouse |
| Clone | REA601 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD8a Antibody, anti-mouse, APC, REAfinity™. Clone REA601 is specific for the mouse CD8a antigen, also known as LY-2 or T8, which is expressed on cytotoxic T cells and at lower levels on subpopulations of dendritic cells and TCRγ/δ+ cells. CD8a is further detected on most thymocytes (CD4+CD8a+ and CD4-CD8+ thymocytes). Cytotoxic T cells and thymocytes express CD8a as heterodimer with CD8b, whereas dendritic cells and TCRγ/δ+ cells express a CD8a/CD8a homodimer. It mediates efficient cell-cell interactions within the immune system. | Additional information: Clone REA601 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CD8, Leu-2, Ly-2, T8, Lyt-2 |
| Gene, Accession # | Gene ID: 12525 |
| Catalog # | 130-117-664 |
| Price | $360 |
| Order / More Info | CD8a, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Liaw, C. W. et al. (1986) Structure, sequence, and polymorphism of the Lyt-2 T cell differentiation antigen gene. J Immunol 137 (3): 1037-1043. | Nakauchi, H. et al. (1985) Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proc. Natl. Acad. Sci. U.S.A. 82 (15): 5126-5130. | Nakauchi, H. et al. (1987) Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. Nucleic Acids Res. 15 (10): 4337-4347. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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