CD294 (CRTH2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD294 (CRTH2), Human |
| Clone | REA598 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD294 (CRTH2) Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA598 recognizes the CD294 antigen, also known as chemoattractant receptor-homologous molecule expressed on T?2 cells (CRTH2). CD294 is a seven-transmembrane G protein-coupled receptor for prostaglandin D2 involved in migration of leukocytes and is expressed on T helper type 2 (T?2) cells, a subpopulation of CD4+ T cells, but not on T?1 cells. The CD294 antigen is highly expressed on peripheral blood basophils and eosinophils. It is also present on a small population of CD8+ T cells and on a subpopulation of dendritic cells (DCs). | Additional information: Clone REA598 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CRTH2 |
| Gene, Accession # | Gene ID: 11251 |
| Catalog # | 130-119-623 |
| Price | $370 |
| Order / More Info | CD294 (CRTH2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Nagata, K. et al. (1999) Selective expression of a novel surface molecule by human T?2 cells in vivo. J Immunol 162: 1278-1286. | Messi, M. et al. (2003) Memory and flexibility of cytokine gene expression as separable properties of human T?1 and T?2 lymphocytes. Nat Immunol 4: 78-86. | Nagata, K. et al. (1999) CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s). FEBS Lett. 459: 195-199. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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