MICA/MICB, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityMICA/MICB, Human
CloneREA1076
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatbiotin conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionMICA/MICB Antibody, anti-human, Biotin, REAfinity™. Clone REA1076 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA and MICB have no association with β2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA and MICB are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells. | Additional information: Clone REA1076 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesMICB, PERB11.2, MICA, PERB11.1
Gene, Accession #Gene ID: 100507436, 4277
Catalog #130-118-894
Price$93
Order / More InfoMICA/MICB, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHouchins, J. P. et al. (1991) DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J. Exp. Med. 173 (4): 1017-1020. | Bauer, S. et al. (1999) Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285: 727-729. | Li, P. et al. (1999) Crystal structure of the MHC class I homolog MIC-A, a γδ T cell ligand. Immunity 10: 577-584.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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