Claudin-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Claudin-4, Human |
| Clone | REA898 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Claudin-4 Antibody, anti-human, Biotin, REAfinity™. Clone REA898 recognizes the human claudin-4 antigen, an integral membrane protein with four transmembrane segments, which is a component of the claudin family of epithelial tight junction proteins. Claudin is found in the intestinal mucosa epithelium and is highly expressed in pancreatic cancer. In association with EphA2 Claudin-4 is inveolved in the regulation of tight juctions and it plays a role in epithelial tissue development. | Additional information: Clone REA898 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CLDN4, CPER, CPE-R, CPETR1, WBSCR8 |
| Gene, Accession # | Gene ID: 1364 |
| Catalog # | 130-114-910 |
| Price | $93 |
| Order / More Info | Claudin-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Michl, P. et al. (2003) Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer. Cancer Res. 63 (19): 6265-6271. | Tanaka, M. et al. (2005) EphA2 phosphorylates the cytoplasmic tail of Claudin-4 and mediates paracellular permeability. J. Biol. Chem. 280 (51): 42375-42382. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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