CD151, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD151, Human
CloneREA265
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatbiotin conjugate
Size30 tests in 300 µL
Concentration1:11
ApplicationsFlow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCD151 Antibody, anti-human, Biotin, REAfinity™. Clone REA265 recognizes the CD151 antigen, a 29 kDa cell surface glycoprotein, which is also known as platelet-endothelial tetraspan antigen 3 (PETA-3) or tetraspanin-24 (Tspan-24). Like other tetraspanin family members, CD151 contains four hydrophobic transmembrane domains, two short cytoplasmic tails, and one small and one large extracellular loop. CD151 is expressed by many different cell types such as platelets, immature hematopoietic cells, megakaryocytes, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, as well as epithelial cells. It complexes with integrins and other transmembrane 4 superfamily proteins and is involved in cellular processes including cell adhesion and regulates integrin trafficking and function. CD151 enhances cell motility, invasion, and metastasis of tumor cells. | Additional information: Clone REA265 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesGP27, MER2, PETA-3, RAPH, SFA1, TSPAN24
Gene, Accession #Gene ID: 977
Catalog #130-103-767
Price$99
Order / More InfoCD151, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesKaramatic, C. V. et al. (2004) CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin. Blood 104 (8): 2217-2223. | Kohno, M. et al. (2002) CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. Int. J. Cancer 97 (3): 336-343. | Chernousov, M. A. et al. (2013) Tetraspanins are involved in Schwann cell-axon interaction. J. Neurosci. Res. 91 (11): 1419-1428.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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