TCR Vβ12, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCR Vβ12, Mouse |
| Clone | REA946 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | Vio Bright B515 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCR Vβ12 Antibody, anti-mouse, Vio® Bright B515, REAfinity™. Clone REA946 recognizes the mouse V beta 12 T cell receptor (TCR Vβ12). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA946 recognizes TCR Vβ12 on mouse strains with b haplotypes (e.g., BALB/c, C3H, and DBA/1). | Additional information: Clone REA946 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TCR Vb12 |
| Gene, Accession # | Gene ID: 100124672, 100124676, 100124674 |
| Catalog # | 130-115-699 |
| Price | $200 |
| Order / More Info | TCR Vβ12, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Vacchio, M. S. and Hodes, R. J. (1989) Selective decreases in T cell receptor V beta expression. Decreased expression of specific V beta families is associated with expression of multiple MHC and non-MHC gene products. J. Exp. Med. 170 (4): 1335-1346. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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