CDw198 (CCR8), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CDw198 (CCR8), Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CDw198 (CCR8), Mouse |
| Clone | REA921 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CDw198 (CCR8) Antibody, anti-mouse, PE, REAfinity™. Clone REA921 recognizes the mouse CDw198 antigen, also known as C-C chemokine receptor type 8 (CCR8). CDw198, a G-protein coupled receptor with seven transmembrane regions, is a member of the beta chemokine receptor family, which binds to the T cell activation gene 3 (TCA-3) and CCL1. CDw198 is primarily found in thymus. It is expressed in activated T?2-polarized cells and NK1.1+ CD4+ T cells, but also in subsets of monocytes, macrophages, and monocyte-derived dendritic cells. CDw198 plays a role in migration of various cell types into inflammatory sites. | Additional information: Clone REA921 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CCR8, CCR-8, CC-CKR-8 |
| Gene, Accession # | Gene ID: 12776 |
| Catalog # | 130-115-377 |
| Price | $71 |
| Order / More Info | CDw198 (CCR8), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Goya, I. et al. (1998) Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3. J Immunol 160 (4): 1975-1981. | Zingoni, A. et al. (1998) The chemokine receptor CCR8 is preferentially expressed in T?2 but not T?1 cells. J Immunol 161 (2): 547-551. | Islam, S. A. et al. (2011) Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T?2 cells. Nat Immunol 12 (2): 167-177. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies