CD300a (LMIR1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD300a (LMIR1), Mouse
CloneREA573
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatbiotin conjugate
Size9 µg in 300 µL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD300a (LMIR1) Antibody, anti-mouse, Biotin, REAfinity™. Clone REA573 recognizes the mouse CD300a antigen, a type I transmembrane protein of the immunoglobulin superfamily, also known as leukocyte mono-Ig-like receptor1 (LMIR1) or inhibitory receptor protein 60 (IRp60). CD300a plays an important regulatory role in cell signaling and immune responses. It is expressed on monocytes, macrophages, neutrophils, mast cells, NK cells, dendritic cells, and on subsets of T and B lymphocytes. | Additional information: Clone REA573 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesCLM-8, Lmir1, MAIR-I, MAIR-Ia, MMAC8, Pigr4, Mcpir1, MAIR-1, IRp60, CMRF-35H
Gene, Accession #Gene ID: 217303
Catalog #130-109-090
Price$31
Order / More InfoCD300a (LMIR1), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBachelet, I. et al. (2005) The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells. J Immunol 175 (12): 7989-7995. | Yotsumoto, K. et al. (2003) Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. J. Exp. Med. 198 (2): 223-233. | Cantoni, C. et al. (1999) Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells. Eur. J. Immunol. 29 (10): 3148-3159. | Kumagai, H. et al. (2003) Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells. Biochem. Biophys. Res. Commun. 307 (3): 719-729.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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