IL-17E, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityIL-17E, Mouse
CloneREA952
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
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DescriptionIL-17E Antibody, anti-mouse, PE, REAfinity™. Clone REA952 recognizes the mouse interleukin 17E (IL-17E) antigen. IL-17 is a family of pro-inflammatory cytokines that plays a central role in adaptive immunity as well as autoinflammatory disorders. Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. IL-17E is suggested to be an important mediator of allergic disease via production of IL-4, IL-5, IL-13, and eotaxin. IL-17E expression is found in low levels in different peripheral tissues, e.g., prostate, testis, trachea, brain, kidney, and lung. | Additional information: Clone REA952 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesIL17E, Interleukin 17E, IL-25, IL25, Interleukin 25
Gene, Accession #Gene ID: 140806
Catalog #130-115-805
Price$71
Order / More InfoIL-17E, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesFort, M. M. et al. (2001) IL-25 induces IL-4, IL-5, and IL-13 and T?2-associated pathologies in vivo. Immunity 15 (6): 985-995. | Hurst, S. D. et al. (2002) New IL-17 family members promote T?1 or T?2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol 169 (1): 443-453. | Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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