CD25, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD25, Mouse |
| Clone | REA568 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | Vio Bright R720 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD25 Antibody, anti-mouse, Vio® Bright R720, REAfinity™. Clone REA568 recognizes the mouse CD25 antigen, the α chain of the IL-2 receptor (IL-2R). IL-2Rα associates with the β chain (CD122) and the γ chain (CD132) to form the functional IL-2R complex. IL-2Rα is expressed on CD4+CD25+ regulatory T cells, activated T and B cells, and to a lesser extent on activated dendritic cells. It is also transiently expressed during T and B cell development. Binding of the CD25 antibody does not impede the binding of IL-2 to its receptor. In combination with CD4, CD25 antibody can be used to identify regulatory T cells (Tregs). | Additional information: Clone REA568 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | IL2RA, IL2R, Ly-43, p55 |
| Gene, Accession # | Gene ID: 16184 |
| Catalog # | 130-127-476 |
| Price | $161 |
| Order / More Info | CD25, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Miller, J. et al. (1985) Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. J Immunol 134 (6): 4212-4217. | Read, S. et al. (2000) Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation. J. Exp. Med. 192 (2): 295-302. | Taniguchi, T. et al. (1993) The IL-2/IL-2 receptor system: a current overview. Cell 73 (1): 5-8. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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