CD83, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD83, Human |
| Clone | HB15 |
| Host Species | Mouse |
| Reactive Species | human, nonhuman primate, other |
| Isotype | IgG1κ |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD83 Antibody, anti-human, PE. The CD83 antibody reacts with a 45 kDa glycoprotein member of the immunoglobulin superfamily of receptors, also known as HB15. In humans, CD83 is expressed on the surface of activated dendritic cells (DCs) and can therefore be used as a marker for the phenotypical characterization of DC maturation. CD83 plays a role in antigen presentation and lymphocyte activation. |
| Immunogen | n/a |
| Other Names | BL11, HB15 |
| Gene, Accession # | Gene ID: 9308 |
| Catalog # | 130-094-181 |
| Price | $310 |
| Order / More Info | CD83, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Zhou, L.-J. et al. (1992) A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily. J Immunol 149: 735-742. | Zhou, L.-J. and Tedder, T. F. (1995) Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J Immunol 154: 3821-3835. | Sallusto, F. and Lanzavecchia, A. (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179: 1109-1118. | Cao, W. et al. (2005) CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells. Biochem. J. 385: 85-93. | Lechmann, M. et al. (2002) CD83 on dendritic cells: more than just a marker for maturation. Trends Immunol. 23: 273-275. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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