WT1, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityWT1, Human/Mouse
CloneREA925
Host SpeciesRecombinant Human
Reactive Specieshuman, mouse
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size200 µL
Concentration1:50
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionWT1 Antibody, anti-human/mouse, FITC, REAfinity™. Clone REA925 recognizes the human and mouse WT1 protein, also known as Wilms Tumor Protein 1 or Wilms tumor suppressor protein. WT1 is a transcription factor with four zinc fingers with distinct splicing isoforms. It plays an important role in cellular development and cell survival, especially in the development of the urogenital system. Furthermore, WT1 has a tumor suppressor and oncogenic role in tumor formation. WT1 is mainly expressed in kidney and on a subset of hematopoietic cells. | Additional Information: Clone REA925 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesWilms tumor protein, WT33
Gene, Accession #Gene ID: 7490, 22431
Catalog #130-115-469
Price$270
Order / More InfoWT1, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesCall, K. M. et al. (1990) Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 60 (3): 509-520. | Hamilton, T. B. et al. (1995) High affinity binding sites for the Wilms' tumour suppressor protein WT1. Nucleic Acids Res. 23 (2): 277-284. | Smolen, G. A. et al. (2004) SUMO-1 modification of the Wilms' tumor suppressor WT1. Cancer Res. 64 (21): 7846-7851.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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