TIM-4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TIM-4, Mouse |
| Clone | REA999 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TIM-4 Antibody, anti-mouse, PE-Vio® 615, REAfinity™. Clone REA999 recognizes the mouse antigen TIM-4, which is also known as T cell immunoglobulin and mucin domain-containing protein 4 or spleen, mucin-containing, knockout of lymphotoxin protein (SMUCKLER). TIM-4 is a member of the TIM gene family, which is involved in a variety of immunity related processes including T cell proliferation and survival, tissue inflammation, and atopy. In mice, eight TIM genes encode the proteins TIM-1 to TIM-8, whereas only three TIM genes are found in humans encoding TIM-1, TIM-3, and TIM-4. In spleen, TIM-4 is expressed on antigen presenting cells such as lymphoid and myeloid dendritic cells and macrophages but not by T or B lymphocytes. |
| Immunogen | n/a |
| Other Names | T-cell immunoglobulin and mucin domain-containing protein 4, TIMD-4, SMUCKLER, TIM4, T-cell membrane protein 4 |
| Gene, Accession # | Gene ID: 276891 |
| Catalog # | 130-116-638 |
| Price | $450 |
| Order / More Info | TIM-4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Shakhov, A. N. et al. (2004) SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling. Eur. J. Immunol. 34 (2): 494-503. | Miyanishi, M. et al. (2007) Identification of Tim4 as a phosphatidylserine receptor. Nature 450 (7168): 435-439. | Rodriguez-Manzanet, R. et al. (2008) TIM-4 expressed on APCs induces T cell expansion and survival. J Immunol 180 (7): 4706-4713. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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