NK1.1, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | NK1.1, Mouse |
| Clone | REA1162 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NK1.1 Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA1162 recognizes the mouse NK1.1 antigen, a single-pass type II membrane protein also known as CD161 or killer cell lectin-like receptor subfamily B member 1. NK1.1 is expressed by natural killer cells and a subset of T cells in the mouse strains C57BL/6, FVB/N, and NZB, but not in the mouse strains AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. It plays a stimulatory role on natural killer cells cytotoxicity. Activation by cross-linking of the receptor induces Ca 2)+ mobilization and interferon-gamma production. | Additional information: Clone REA1162 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | NKR-P1 40, CD161c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C |
| Gene, Accession # | Gene ID: 17059 |
| Catalog # | 130-120-510 |
| Price | $119 |
| Order / More Info | NK1.1, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Giorda, R. et al. (1992) Genomic structure and strain-specific expression of the natural killer cell receptor NKR-P1. J Immunol 149 (6): 1957-1963. | Stenstrom, M. et al. (2005) Natural killer T-cell populations in C57BL/6 and NK1.1 congenic BALB.NK mice-a novel thymic subset defined in BALB.NK mice. Immunology 114 (3): 336-345. | Ruiz, A. L. et al. (2014) NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response. Nat Commun. 5: 5150. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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