CD31, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD31, Mouse
CloneREAL260
Host SpeciesRecombinant Human
Reactive Speciesmouse
Isotypen/a
Formatallophycocyanin (APC) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD31 Antibody, anti-mouse, APC, REAlease®. Clone REAL260 is an antibody fragment derived from the full CD31 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL260 recognizes the cell surface protein CD31. The murine CD31 antigen is also known as PECAM-1. The encoded protein is a single-pass type I membrane protein containing six Ig-like C2-type (immunoglobulin-like) domains and functions as cell adhesion molecule. CD31 is present on mature endothelial cells as well as on most leukocyte subtypes and platelets where the expression level can vary. Besides its function in exhibiting adhesive properties, the protein is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
Immunogenn/a
Other NamesPECAM1, Pecam, EndoCAM, GPIIa
Gene, Accession #n/a
Catalog #130-115-988
Price$109
Order / More InfoCD31, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesXie, Y. and Muller, W. A. (1993) Molecular cloning and adhesive properties of murine platelet/endothelial cell adhesion molecule 1. Proc. Natl. Acad. Sci. U.S.A. 90 (12): 5569-5573. | Woodfin, A. et al. (2007) PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler. Thromb. Vasc. Biol. 27 (12): 2514-2523. | van Buul, J. D. and Hordijk, P. L. (2008) Endothelial signaling by Ig-like cell adhesion molecules. Transfus. Clin. Biol. 15 (1-2): 3-6.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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