TTF-1, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TTF-1, Human/Mouse |
| Clone | REA1090 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TTF-1 Antibody, anti-human/mouse, APC, REAfinity™. TTF-1 (thyroid transcripton factor-1, NKX2.1) is a homeodomain-containing transcription factor. It controls cell differentiation of telencephalic cells and is essential for proper ventral forebrain development. Furthermore, it is a key factor in the morphogenesis and differentiation of the thyroid and lung. TTF-1 is detected in primary lung adenocarcinomas and small cell carcinomas and is absent in colon and breast carcinomas. Analysis of TTF-1 expression is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating from other tumors. | Additional information: Clone REA1090 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | NKX2A, TITF1, TTF1, NKX2-1, NKx2.1, Thyroid transcription factor 1 |
| Gene, Accession # | Gene ID: 7080, 21869 |
| Catalog # | 130-118-448 |
| Price | $142 |
| Order / More Info | TTF-1, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tanaka, H. et al. (2007) Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1. Cancer Res. 67 (13): 6007-6011. | Li, Y. et al. (2013) NKX2-1 activation by SMAD2 signaling after definitive endoderm differentiation in human embryonic stem cell. Stem Cells Dev. 22 (9): 1433-1442. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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