CD11c, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD11c, Human |
| Clone | REA618 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | VioBlue conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD11c Antibody, anti-human, VioBlue®, REAfinity™. Clone REA618 recognizes the human CD11c antigen, a 145-150 kDa type I transmembrane glycoprotein, which is also known as integrin αX or CR4. It is expressed on monocytes, macrophages, NK cells, granulocytes, myeloid dendritic cells (MDCs), and subsets of T and B cells. On myeloid dendritic cells, CD11c is highly expressed on type 1 myeloid dendritic cells (CD1c (BDCA-1)+ CD123low MDC1s) and low on type 2 myeloid dendritic cells (CD1c (BDCA-1)- CD123- MDC2s). CD11c, also known as integrin integrin αX or CR4, has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b. | Additional information: Clone REA618 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | 95, CR4, integrin αX, ITGAX, p150 |
| Gene, Accession # | Gene ID: 3687 |
| Catalog # | 130-120-032 |
| Price | $355 |
| Order / More Info | CD11c, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Dzionek, A. et al. (2000) BDCA-2, BDCA-3, BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 165: 6037-6046. | Bendiss-Vermare, N. et al. (2001) Human thymus contains IFN-alpha-producing CD11c-, myeloid CD11c+, and mature interdigitating dendritic cells. J. Clin. Invest. 107: 835-844. | Barclay, A. N. et al. (1997) In: The Leukocyte Antigen Facts Book, Academic Press, San Diego, CA. (2nd edition): 161-162. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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