CD255 (TWEAK), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD255 (TWEAK), Human
CloneCARL-1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG3κ
Formatbiotin conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD255 (TWEAK) Antibody, anti-human, Biotin. Clone CARL-1 reacts with the type II transmembrane protein CD255, also known as TWEAK, belonging to the TNF superfamily. It exists as membrane-bound and secreted form and is expressed on most tissues but not or weakly on hematopoietic lineage lines. TWEAK interacts with its receptor APO-3, which promotes inerleukin 8 (IL-8) secretion, activation of NF-κB, and endothelial cell proliferation and apoptosis.
Immunogenn/a
Other NamesTNFSF12, APO3L, Dr3lg, TWEAK
Gene, Accession #Gene ID: 8742
Catalog #130-098-926
Price$264
Order / More InfoCD255 (TWEAK), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesKaplan, M. J. et al. (2000) TRAIL (Apo2 Ligand) and TWEAK (Apo3 Ligand) mediate CD4+ T cell killing of antigen-presenting macrophages. J Immunol 164: 2897- 2904. | Chicheportiche, Y. et al. (1997) TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J. Biol. Chem. 272: 32401 -32410. | Lynch, C. N. et al. (1999) TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274: 8455-8459.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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