TCR Vα2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityTCR Vα2, Mouse
CloneREA679
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
FormatVioBlue conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionTCR Vα2 Antibody, anti-mouse, VioBlue®, REAfinity™. Clone REA679 recognizes the mouse Vα2 T cell receptor (TCR Vα2) of mice having the a, b, and c haplotypes. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules. | Additional information: Clone REA679 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesTCR Va2, TCR alpha2
Gene, Accession #Gene ID: 100042372
Catalog #130-110-301
Price$140
Order / More InfoTCR Vα2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesKubo, R. T. et al. (1989) Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol 142 (8): 2736-2742. | Gregoire, C. et al. (1991) Engineered secreted T-cell receptor alpha beta heterodimers. Proc. Natl. Acad. Sci. U.S.A. 88 (18): 8077-8081.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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