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Antigenic Specificity | Cytochrome c, Human/Mouse/Rat |
Clone | REA702 |
Host Species | Recombinant Human |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytochrome c Antibody, anti-human/mouse/rat, FITC, REAfinity™. Clone REA702 recognizes the human, mouse, and rat cytochrome c, a 15 kDa hemeprotein located in the intermembrane of the mitochondrion. Cytochromes are involved in cell respiration, photosynthesis, and other biochemical reactions. Cytochrome c plays also a role in apoptosis, by release to cytoplasma and binding Apaf-1 which activates procaspase 9. Cytochrome c is found in plants, animals, and many unicellular organisms and catalyzes the electron transfer from reduced cytochrome c to oxygen. | Additional information: Clone REA702 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Cyt c |
Gene, Accession # | Gene ID: 54205, 13063, 25309 |
Catalog # | 130-111-178 |
Price | $264 |
Order / More Info | Cytochrome c, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Margoliash, E. (1963) Primary structure and evolution of cytochrome c. Proc. Natl. Acad. Sci. U.S.A. 50: 672-679. | Ferguson, H. A. et al. (2003) UV-induced apoptosis is mediated independent of caspase-9 in MCF-7 cells: a model for cytochrome c resistance. J. Biol. Chem. 278 (46): 45793-45800. | Tafani, M. et al. (2002) Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. J. Biol. Chem. 277 (12): 10073-10082. |