Edit |   |
---|---|
Antigenic Specificity | CD29, Human |
Clone | TS2/16 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1κ |
Format | PE-Vio 770 conjugate |
Size | 30 tests in 300 µL |
Concentration | 1:11 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD29 Antibody, anti-human, PE-Vio® 770. Clone TS2/16 reacts with CD29, a 130 kDa single-pass type I membrane protein. CD29 is also known as integrin β1 or GPIIa. It forms heterodimers with integrins α1-11 and αV to form functional integrin receptors which bind several cell surface and extracellular molecules such as collagen, fibronectin, laminin, VCAM1, cytotactin, osteopontin, epiligrin, thrombospondin, etc. The cytoplasmic domain of CD29 can interact with cytoskeletal proteins and signaling molecules. In humans, CD29 can be found in four different isoforms (β1A, β1B, β1C, β1D). | |
Immunogen | n/a |
Other Names | ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB |
Gene, Accession # | n/a |
Catalog # | 130-101-281 |
Price | $170 |
Order / More Info | CD29, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Brakebusch, C. et al. (1997) Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules. J. Cell. Sci. 110: 2895-2904. | Altruda, F. et al. (1990) A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing. Gene 95: 261-266. | Shih, D. T. et al. (1993) Structure/function analysis of the integrin beta 1 subunit by epitope mapping. J. Cell Biol. 122 (6): 1361-1371. |