CD352 (NTB-A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD352 (NTB-A), Mouse
CloneREA1097
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
FormatPE-Vio 615 conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD352 (NTB-A) Antibody, anti-mouse, PE-Vio® 615, REAfinity™. Clone REA1097 recognizes the mouse CD352 antigen, a single-pass type I membrane protein also known as SLAM family member 6 (SLAM6), NK-, T-, and B-cell antigen (NTB-A) or Ly108 belonging to the CD2 subfamily of the immunoglobulin superfamily. It is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. CD352 plays a role in NK cell cytotoxicity and T cell cytokine responses. It controls neutrophil functions and serves as a regulator of both innate and adaptive immune responses. | Additional information: Clone REA1097 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesSLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6
Gene, Accession #Gene ID: 30925
Catalog #130-118-728
Price$156
Order / More InfoCD352 (NTB-A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesPeck, S. R. et al. (2000) Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics 52 (1-2): 63-72. | Howie, D. et al. (2005) Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J Immunol 174 (10): 5931-5935. | Griewank, K. et al. (2007) Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27 (5): 751-762.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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