CCL3 (MIP-1α), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCCL3 (MIP-1α), Mouse
CloneREA355
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsIntracellular flow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCCL3 (MIP-1α) Antibody, anti-mouse, PE, REAfinity™. Clone REA355 recognizes the mouse C-C motif chemokine 3 (CCL3) antigen also known as Macrophage inflammatory protein 1 α (MIP-1a). CCL3 is a cytokine belonging to the members of the β (CC) subfamily of chemokines. It is produced by T cells, B cells, Langerhans cells, neutrophils and macrophages. CCL3 is involved in activation and recruitment of lymphocytes, monocytes, and granulocytes during acute inflammation and plays a role as a chemoattractant of monocytes, B cells, eosinophils and cytotoxic T cells. It has been identified as a stem cell inhibitory factor that can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. The functional receptor for CCL3 has been identified as CCR1 and CCR5. CCL3 deficient mice showed increased resistance to viral-induced mortality following infection with HSV-1. | Additional information: Clone REA355 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesLD78alpha, MIP1-alpha, MIP1A, Scya3, L2G25B, SIS-α, Small-inducible cytokine A3, TY-5
Gene, Accession #Gene ID: 20302
Catalog #130-105-266
Price$66
Order / More InfoCCL3 (MIP-1α), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBernardini, G. et al. (2008) CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets. Blood 111 (7): 3626-3634. | Fujita, H. et al. (2004) Expression and regulation of RANTES/CCL5, MIP-1alpha/CCL3, and MIP-1beta/CCL4 in mouse Langerhans cells. J. Invest. Dermatol. 122 (5): 1331-1333. | Grove, M. et al. (1990) Sequence of the murine haemopoietic stem cell inhibitor/macrophage inflammatory protein 1 alpha gene. Nucleic Acids Res. 18 (18): 5561.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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