CD107b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD107b, Human
CloneH4B4
Host SpeciesMouse
Reactive Specieshuman, nonhuman primate
IsotypeIgG1κ
FormatAPC-Vio 770 conjugate
Size30 tests in 300 µL
Concentration1:10
ApplicationsIntracellular flow cytometry
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DescriptionCD107b Antibody, anti-human, APC-Vio® 770. The monoclonal antibody H4B4 reacts with human CD107b, also known as lysosomal-associated membrane protein-2 (LAMP-2), which is a 120 kDa highly glycosylated type I transmembrane protein. It is widely located in lysosomal/endosomal membranes in a high variety of cell types and also expressed on degranulating T cells, activated platelets, and some tumor cell lines. CD107b is involved in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation as well as in tumor cell metastasis.
Immunogenn/a
Other NamesLAMP-2, LAMPB, LGP110
Gene, Accession #Gene ID: 3920
Catalog #130-103-898
Price$151
Order / More InfoCD107b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesGrutzkau, A. et al. (2004) LAMP-1 and LAMP-2, but not LAMP-3, are reliable markers for activation-induced secretion of human mast cells. Cytometry A 61 (1): 62-68. | Carlsson, S. R. et al. (1988) Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan. J. Biol. Chem. 263: 18911-18919. | Betts, M. R. et al. (2004) Detection of T-cell degranulation: CD107a and b. Method Cell Biol. 75: 497-512.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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