CD268, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD268, Mouse |
| Clone | REA1217 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD268 Antibody, anti-mouse, APC, REAfinity™. Clone REA1217 recognizes the CD268 protein, also known as B cell activation factor receptor (BAFF-R), which is a type III transmembrane TNF receptor family member. CD268 is expressed at high levels on resting B cells, at lower levels on activated B cells, and on a small subset of activated/memory T cells. BAFF, also known as BLys, mediates costimulatory responses in peripheral B and T cells. BAFF is a key regulator for B cell differentiation as well as survival and activation of peripheral B cell populations. Accordingly, CD268 appears to be particularly involved in the regulation of normal B cell survival and maturation, but also in the pathophysiology of aggressive B cell malignancies and autoimmune diseases. | Additional information: Clone REA1217 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | BAFF-R, BLyS receptor 3, TNFRSF13c, BAFFR, Bcmd, BR3 |
| Gene, Accession # | Gene ID: 72049 |
| Catalog # | 130-123-434 |
| Price | $91 |
| Order / More Info | CD268, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Thompson, J. S. et al. (2001) BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293 (5537): 2108-2111. | Ng, L. G. et al. (2006) BAFF costimulation of Toll-like receptor-activated B-1 cells. Eur. J. Immunol. 36 (7): 1837-1846. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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