Cytokeratin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Edit | |
|---|---|
| Antigenic Specificity | Cytokeratin, Human |
| Clone | REAL648 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cytokeratin Antibody, anti-human, PE, REAdye_lease™. Clone REAL648 is an antibody fragment derived from the full Cytokeratin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL648 recognizes Pan-Cytokeratin. Cytokeratins are polypeptides with keratin-containing intermediate filaments, which ensure form stability and cohesiveness. Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions and are involved in intracellular signaling pathways. | Anti-Cytokeratin detects cytokeratins which are expressed in normal and abnormal human tissues in epithelial cells and carcinomas. Anti-Cytokeratin is used to differentiate between epithelial carcinoma and non-epithelial malignancies. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | 130-123-087 |
| Price | $490 |
| Order / More Info | Cytokeratin, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Makin, C. A. et al. (1984) Monoclonal antibody to cytokeratin for use in routine histopathology. J Clin Pathol 37: 975-983. | Eichner, R. et al. (1984) Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J. Cell Biol. 98 (4): 1388-1396. | Balasubramanian, P. et al. (2012) Multiparameter analysis, including EMT markers, on negatively enriched blood samples from patients with squamous cell carcinoma of the head and neck. PLoS One 7 (7): . | Xin, H. et al. (2014) Establishment and characterization of 7 novel hepatocellular carcinoma cell lines from patient-derived tumor xenografts. PLoS One 9 (1): e85308. | Gown, A. M. et al. (1985) Monoclonal antibodies to human intermediate filament proteins. III. Analysis of tumors. Am. J. Clin. Pathol. 84 (4): 413-424. | Battifora, H. (1988) Clinical applications of the immunohistochemistry of filamentous proteins. Am J Surg Pathol 12: 24-42. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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