CD323 (JAM3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD323 (JAM3), Human |
| Clone | REA429 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD323 (JAM3) Antibody, anti-human, APC, REAfinity™. Clone REA429 recognizes the human CD323 antigen, a single-pass type I membrane protein, which is also known as junctional adhesion molecule 3 (JAM3) or JAM-C. CD323 is a member of the junctional adhesion molecule family and plays a role in leukocyte migration and cell-cell adhesion. CD323 expression is found on endothelial cells and human platelets. It is expressed at desmosomes but not at tight junctions. CD323 is also expressed at low levels on T cells and is upregulated upon activation. | Additional information: Clone REA429 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | JAM-3, JAM-C, JAM-2 |
| Gene, Accession # | Gene ID: 83700 |
| Catalog # | 130-106-462 |
| Price | $325 |
| Order / More Info | CD323 (JAM3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Arrate, M. P. et al. (2001) Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor. J. Biol. Chem. 276 (49): 45826-45832. | Cunningham, S. A. et al. (2002) JAM2 interacts with alpha4beta1. Facilitation by JAM3. J. Biol. Chem. 277 (31): 27589-27592. | Mochida, G. H. et al. (2010) A homozygous mutation in the tight-junction protein JAM3 causes hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Am. J. Hum. Genet. 87 (6): 882-889. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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