CD31, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD31, Human |
| Clone | REA730 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio R667 conjugate |
| Size | 600 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD31 Antibody, anti-human, Vio® R667, REAfinity™. Clone REA730 recognizes the human CD31 antigen, also known as PECAM-1. CD31 is a member of the immunoglobulin superfamily and is involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is a 120-140 kDa single-chain transmembrane glycoprotein expressed on endothelial cells, monocytes, platelets, granulocytes, and several lymphocyte subsets. During maturation of CD4+ T cells, the expression of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture. | Additional information: Clone REA730 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | PECAM-1, EndoCAM, GPIIa, PECA1 |
| Gene, Accession # | Gene ID: 5175 |
| Catalog # | 130-131-144 |
| Price | $666 |
| Order / More Info | CD31, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Newman, P. J. et al. (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247 (4947): 1219-1222. | Stockinger, H. et al. (1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31. J Immunol 145 (11): 3889-3897. | Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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