CD140a, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD140a, Mouse |
| Clone | REA637 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD140a Antibody, anti-mouse, PE, REAfinity™. Clone REA637 recognizes the mouse CD140a antigen, a single-pass type I membrane protein, also known as platelet-derived growth factor receptor alpha (PDGFRα). CD140a is a receptor tyrosine kinase that forms homodimers or heterodimers with CD140b (PDGFRβ). Receptor dimerization and transphosphorylation at tyrosine residues activates the intracellular kinase activity. CD140a is broadly expressed in embryonic tissue, mostly in cells of mesodermal origin in adult tissue, and embryonic stem cell-derived cardiomyogenic cells. Expression of CD140a is associated with various malignancies. | Additional information: Clone REA637 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | PDGF-R-alpha, PDGFR-alpha, PDGFR-α |
| Gene, Accession # | Gene ID: 18595 |
| Catalog # | 130-122-019 |
| Price | $68 |
| Order / More Info | CD140a, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Takakura, N. et al. (1997) PDGFRα expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal antibody anti-mouse PDGFR alpha antibody APA5. J. Histochem. Cytochem. 45 (6): 883-893. | Ntokou, A. et al. (2015) Characterization of the platelet-derived growth factor receptor α-positive cell lineage during murine late lung development. Am. J. Physiol. Lung Cell Mol. Physiol. 309 (9): L942-948. | Zhou, Q. et al. (2015) Cardiac telocytes are double positive for CD34/PDGFR?α. J. Cell. Mol. Med. 19 (8): 2036-2042. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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