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Antigenic Specificity | CD36L1 (SR-BI), Human |
Clone | REA716 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD36L1 (SR-BI) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA716 recognizes the human CD36L1 antigen, an integral membrane protein, also known as SR-BI. CD36L1 is widly expressed, e.g. on macrophages, dendritic cells, adrenocortical cells, adipocytes, and trophoblastic cells. In hepatocytes, CD36L1 acts as a receptor for hepatitis C. It has been reported, that CD36L1 is able to bind HCV envelope glycoprotein E2, participate in entry of HCV pseudotype particles, and modulate HCV infection. Furthermore, CD36L1 is a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, vitamin E, phosphatidylserine, and apoptotic cells. | Additional information: Clone REA716 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | SRB1, CLA-1, CD36 antigen-like 1, SR-BI, SCARB1 |
Gene, Accession # | Gene ID: 949 |
Catalog # | 130-131-019 |
Price | $161 |
Order / More Info | CD36L1 (SR-BI), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Scarselli, E. et al. (2002) The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21 (19): 5017-5025. | Zeisel, M. B. et al. (2007) Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology 46 (6): 1722-1731. | Valacchi, G. et al. (2011) Scavenger receptor class B type I: a multifunctional receptor. Ann. N. Y. Acad. Sci. 1229: . |