CD158i (KIR2DS4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD158i (KIR2DS4), Human
CloneJJC11.6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
Formatallophycocyanin (APC) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD158i (KIR2DS4) Antibody, anti-human, APC. Clone JJC11.6 recognizes CD158i (KIR2DS4), a member of the killer immunoglobulin-like receptor (KIR) family expressed on natural killer (NK) cells. CD158i (KIR2DS4) provides an activation signal for NK lytic activity upon interaction with its ligand, HLA-Cw4, in an antigen-independent manner. | KIRs are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. The receptor family can be subdivided functionally according to the length of their cytoplasmic tail in inhibitory and activating KIRs.
Immunogenn/a
Other NamesKIR2DS4
Gene, Accession #Gene ID: 3809
Catalog #130-092-681
Price$325
Order / More InfoCD158i (KIR2DS4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesKratz, G. et al. (2004) MHC Class I-independent recognition of NK-activating receptor KIR2DS4. J Immunol 173: 1819-1825. | Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52. | Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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