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Antigenic Specificity | CD182 (CXCR2), Mouse |
Clone | REA942 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD182 (CXCR2) Antibody, anti-mouse, PE, REAfinity™. Clone REA942 recognizes the mouse CD182 (CXCR2) antigen, which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. Binding of interleukin 8 (IL-8) to CD182 leads to the activation of neutrophil granulocytes. CD182 is also a ligand for CXCL3, GRO/MGSA, and NAP-2. | Additional information: Clone REA942 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CXC-R2, CXCR-2, IL-8R B, CXCR2, CMKAR2, Gpcr16, Il8rb |
Gene, Accession # | Gene ID: 12765 |
Catalog # | 130-115-540 |
Price | $240 |
Order / More Info | CD182 (CXCR2), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bozic, C. R. et al. (1994) The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization. J. Biol. Chem. 269 (47): 29355-29358. | Nolan, K. F. et al. (2004) IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals. J Immunol 172 (4): 2201-2209. |