CD158b2 (KIR2DL3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD158b2 (KIR2DL3), Human |
| Clone | REA147 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PerCP-Vio 700 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD158b2 (KIR2DL3) Antibody, anti-human, PerCP-Vio® 700, REAfinity™. Clone REA147 recognizes CD158b2, a killer cell immunoglobulin-like inhibitory receptor (KIR). Expressed by natural killer (NK) cells and a subset of T cells, KIR family of receptors are transmembrane glycoproteins and interact with MHC class I molecules. This interaction allows the KIR receptors to modulate the killing function of cells bearing them. The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by the length (long (L) or short (S)) of the cytoplasmic domain. KIR proteins with the long cytoplasmic domain, such as CD158b2, transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM). | Additional information: Clone REA147 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3 |
| Gene, Accession # | Gene ID: 3804 |
| Catalog # | 130-126-120 |
| Price | $141 |
| Order / More Info | CD158b2 (KIR2DL3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Gendzekhadze, K. et al. (2009) Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands. Proc. Natl. Acad. Sci. U.S.A. 106: 18692-18697. | Keaney, L. et al. (2004) Investigation of killer cell immunoglobulin-like receptor gene diversity III. KIR2DL3. Tissue Antigens 64 (2): 188-194. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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