Melanocyte PMEL, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Melanocyte PMEL, Human |
| Clone | REA927 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | 1:50 |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Melanocyte PMEL Antibody, anti-human, PE, REAfinity™. Clone REA927 recognizes the human Melanocyte PMEL antigen (Melanocyte premelanosome protein), which is located in fetal and neonatal melanocytes and junctional nevi. Melanocyte PMEL is a marker for melanocytic tumors such as melanomas, it is not expressed in normal tissues nor in carcinomas. Melanosome, also known as Melanocyte protein Pmel 17, plays an essential role in the biogenesis of melanosomes and maturation of melanosomes. | Additional Information: Clone REA927 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Pmel 17, Melanocyte protein PMEL, premelanosome protein, gp100 |
| Gene, Accession # | Gene ID: 6490 |
| Catalog # | 130-115-473 |
| Price | $315 |
| Order / More Info | Melanocyte PMEL, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Gown, A. M. et al. (1986) Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am. J. Pathol. 123 (2): 195-203. | Kawakami, Y. et al. (1994) Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc. Natl. Acad. Sci. U.S.A. 91 (14): 6458-6462. | Chi, A. et al. (2006) Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. J. Proteome Res. 11 (5): 3135-3144. | Kodet, O. et al. (2013) Cultivation-dependent plasticity of melanoma phenotype. Tumour Biol 34 (6): 3345-3355. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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