CD148, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD148, Human |
| Clone | REA204 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD148 Antibody, anti-human, Biotin, REAfinity™. Clone REA204 recognizes CD148, a receptor type protein tyrosine phosphatase (PTP) belonging to the type III family of PTPs. CD148 is characterized by an extracellular domain with eight fibronectin type III repeats, a trans-membrane region, and a single cytosolic catalytic domain. Expression of CD148 is found on mature thymocytes, peripheral T cells, B cells, NK cells, granulocytes, macrophages, DC subpopulations, epithelial and endothelial cells, and fibroblasts. An upregulated expression of CD148 on human peripheral T cells is observed upon TCR stimulation. CD148 via regulating the phosphorylation status of substrates such as PDGFR, p120 catenin (CTND1), and SRC kinase, plays vital role in many cellular functions. | Additional information: Clone REA204 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | PTPRJ, DEP1, HPTPeta, R-PTP-ETA, SCC1 |
| Gene, Accession # | Gene ID: 5795 |
| Catalog # | 130-101-248 |
| Price | $99 |
| Order / More Info | CD148, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tangye, S. G. et al. (1998) CD148: A receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation. J Immunol 161: 3249-3255. | de la Fuente-Garcia, M. A. et al. (1998) CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes. Blood 91: 2800-2809. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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