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Antigenic Specificity | CD45RA, Human |
Clone | REA562 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45RA Antibody, anti-human, PE, REAfinity™. Clone REA562 recognizes the human CD45RA antigen, which is expressed on naive CD4+ and CD8+ T cells as well as on CD8+ effector T cells. CD45RA is also present on subsets of B and NK cells as well as on plasmacytoid dendritic cells. The CD45RA antibody recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase. | Additional information: Clone REA562 displays negligible binding to Fc receptors |
Immunogen | n/a |
Other Names | Ptprc, B220, CD45R, GP180, L-CA, LY5, T200 |
Gene, Accession # | Gene ID: 5788 |
Catalog # | 130-113-928 |
Price | $121 |
Order / More Info | CD45RA, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Braun, T. et al. (2012) Effector CD4+CD45RA-CD25brightFoxp3bright regulatory T cell (eTreg) distribution is significantly impaired in chronic myelomonocytic leukemia (CMML) and correlates with TET 2 mutational status. Blood 120: 2808-2808. | Baba, N. et al. (2010) Interplay between CD45RA+ regulatory T cells and TNF-α in the regulation of human T?17 differentiation. Int. Immunol. 22: 237-244. | Cantisan, S. et al. (2010) CD45RA expression on HCMV-specific effector memory CD8+ T cells is associated with the duration and intensity of HCMV replication after transplantation. Clin. Immunol. 137 (1): 81-88. |