fMLP receptor, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityfMLP receptor, Human
CloneREA169
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsIntracellular flow cytometry
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DescriptionfMLP receptor Antibody, anti-human, APC, REAfinity™. Clone REA169 recognizes N-formyl-L-methionyl-L-leucyl-phenylalanine receptor (fMLP receptor), which is a seven transmembrane G-protein coupled receptor. fMLP receptor binds formylated peptides such as fMLP, which originate from degraded bacterial or mitochondrial proteins and mediate inflammatory reactions, activation of neutrophils and trafficking of leukocytes to the site of inflammation. Expression of fMLP receptor is mainly found on leukocytes, neutrophils and monocytes. | Additional Information: Clone REA169 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesFPR1, FMLP, FPR
Gene, Accession #Gene ID: 2357
Catalog #130-100-812
Price$325
Order / More InfofMLP receptor, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesPaclet, M. H. et al. (2004) N-Formyl peptide receptor subtypes in human neutrophils activate L-plastin phosphorylation through different signal transduction intermediates. Biochem. J. 377: 469-477.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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