CD40, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD40, Human |
| Clone | REA733 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | PerCP-Vio 700 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD40 Antibody, anti-human, PerCP-Vio® 700, REAfinity™. Clone REA733 recognizes the human CD40 antigen, a transmembrane receptor of the tumor necrosis factor gene superfamily. CD40 is a costimulatory protein constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages and on endothelial, smooth muscle cells, and fibroblasts. The binding of CD40 to CD154 (CD40L) on T helper cells activates antigen presenting cells and enhances the expression of cytokines, chemokines, matrix metalloproteinases, growth factors, and adhesion molecules. CD40 has been shown to interact with members of the TRAF family. | Additional information: Clone REA733 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Bp50, CD40L receptor, CDW40 |
| Gene, Accession # | Gene ID: 958 |
| Catalog # | 130-128-721 |
| Price | $141 |
| Order / More Info | CD40, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Stamenkovic, I. et al. (1989) A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8 (5): 1403-1410. | Sato, T. et al. (1995) A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40. FEBS Lett. 358 (2): 113-118. | Chatzigeorgiou, A. et al. (2009) CD40/CD40L signaling and its implication in health and disease. Biofactors 35 (6): 474-483. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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