TCR Vβ11, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCR Vβ11, Mouse |
| Clone | REA657 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCR Vβ11 Antibody, anti-mouse, APC, REAfinity™. Clone REA657 recognizes the mouse V beta 11 T cell receptor (TCR Vβ11). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCR Vβ11 is a variant of the TCR β chain and is expressed on mouse strains with the b haplotype in the TCR β gene complex, including C57BL/6 and B10, but not on mice strains with the a haplotype, including C57L, SJL, and SWR. | Additional information: Clone REA657 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TCR Vb11, TCR Vbeta11 |
| Gene, Accession # | Gene ID: 100124671 |
| Catalog # | 130-109-984 |
| Price | $61 |
| Order / More Info | TCR Vβ11, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Bill, J. et al. (1989) The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells. J. Exp. Med. 169 (4): 1405-1419. | Davis, M. M. et al. (1998) Ligand recognition by alpha beta T cell receptors. Annu. Rev. Immunol. 16: 523-544. | DiRienzo, C. G. et al. (2007) T-cell receptor V(alpha) usage by effector CD4+Vbeta11+ T cells mediating graft-versus-host disease directed to minor histocompatibility antigens. Biol. Blood Marrow Transplant. 13 (3): 265-276. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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