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Antigenic Specificity | Galectin-3, Human/Mouse |
Clone | REA1072 |
Host Species | Recombinant Human |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | Vio B515 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Galectin-3 Antibody, anti-human/mouse, Vio® B515, REAfinity™. Clone REA1072 recognizes mouse and human galectin-3, which is a 32 kDa protein belonging to the beta-galactoside-binding animal lectin family. Galectin-3, also known as Mac-2, has an IgE-binding activity and is localized in Kupffer cells, macrophages, human peripheral blood monocytes, and murine activated T cells. An upregulated expression of galectin-3 is observed during cell proliferation, differentiation, and inflammation. | Additional information: Clone REA1072 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | LGALS3, CBP35, GAL3, GALBP, L31, LGALS2, Mac-2 |
Gene, Accession # | Gene ID: 16854, 3958 |
Catalog # | 130-129-263 |
Price | $134 |
Order / More Info | Galectin-3, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Springer, T. A. et al. (1981) Monoclonal antibody analysis of complex biological systems. Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface. J. Biol. Chem. 256: 3833-3839. | Ho, M. K. and Springer, T. A. et al. (1982) Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J Immunol 128: 1221-1228. | Liu, F. T. et al. (1995) Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am. J. Pathol. 147 (4): 1016-1028. | Joo, H. G. et al. (2001) Expression and function of galectin-3, a β-galactoside-binding protein in activated T lymphocytes. J. Leukoc. Biol. 69: 555-564. |