Edit |   |
Antigenic Specificity | CD51/CD61, Human |
Clone | REA1099 |
Host Species | Recombinant Human |
Reactive Species | human, other |
Isotype | IgG1 |
Format | Vio Bright B515 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD51/CD61 Antibody, anti-human, Vio® Bright B515, REAfinity™. Clone REA1099 recognizes the human heterodimeric complex CD51/CD61, also known as integrin αv/β3. The dimers are expressed on melanoma cells, endothelial cells, on osteoclasts, and in a very low density on platelets. The CD51/CD61 complex mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, osteopontin, and collagen. | Additional information: Clone REA1099 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ITGAV, MSK8, VNRA, VTNR, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3 |
Gene, Accession # | Gene ID: 3685, 3690 |
Catalog # | 130-119-058 |
Price | $470 |
Order / More Info | CD51/CD61, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Athanasou, N. A. et al. (1990) New sites of cellular vitronectin receptor immunoreactivity detected with osteoclast-reacting monoclonal antibodies 13C2 and 23C6. Bone Miner. 8 (1): 7-22. | Chuntharapai, A. et al. (1993) Blocking monoclonal antibodies to alpha V beta 3 integrin: a unique epitope of alpha V beta 3 integrin is present on human osteoclasts. Exp. Cell Res. 205 (2): 345-352. |