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Antigenic Specificity | TCR Vβ8, Mouse |
Clone | REA684 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vβ8 Antibody, anti-mouse, Biotin, REAfinity™. Clone REA684 recognizes the mouse Vβ8 T cell receptor (TCR Vβ8) of mice having the b haplotype. Vβ8 is a variant of the TCR β chain that associates with the TCR α chain. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vβ8 is expressed on a subset of α/β T cells. | Additional information: Clone RE684 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Gene ID: 100124664 |
Catalog # | 130-110-932 |
Price | $202 |
Order / More Info | TCR Vβ8, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Haskins, K. et al. (1984) The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 160 (2): 452-471. | White, J. et al. (1989) The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell 56 (1): 27-35. | Jiang, Y. et al. (1996) In vitro effects of HgCl2 on murine lymphocytes. II. Selective activation of T cells expressing certain V beta TCR. Int. Immunol. 8 (11): 1729-1736. |