CD63, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD63, Human |
| Clone | REA1055 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD63 Antibody, anti-human, PE, REAfinity™. Clone REA1055 recognizes the human CD63 antigen, a type III glycoprotein belonging to the tetraspanin family of proteins, which are characterized by four membrane spanning domains. Tetraspanins via various homotypic and heterotypic interactions regulate the spatial location and trafficking of associated transmembrane partners, eventually regulating and co-ordinating various signaling pathways. CD63, like other tetraspanins, is present in the plasma membrane and membrane of various subcellular compartments such as late endosomes, lysososmes, cytotoxic granules of T lymphocytes, the crystalloid granules of eosinophils, the secretory granules of basophils, and mast cells. Interaction partners of CD63 include MHC class II molecules in immature dendritic cells and B lymphocytes, FcεRI in basophils and mast cells, etc. | Additional information: Clone REA1055 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | LAMP-3, ME491, MLA1, OMA81H, Tspan30, LIMP1 |
| Gene, Accession # | Gene ID: 967 |
| Catalog # | 130-118-150 |
| Price | $121 |
| Order / More Info | CD63, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Vischer, U. M. and Wagner, D. D. (1993) CD63 is a component of Weibel-Palade bodies of human endothelial cells. Blood 82: 1184-1191. | Mahmudi-Azer, S. et al. (2002) Translocation of the tetraspanin CD63 in association with human eosinophil mediator release. Blood 99: 4039-4047. | Pols, M. S. and Klumperman, J. (2009) Trafficking and function of the tetraspanin CD63. Exp. Cell Res. 315 (9): 1584-1592. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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