CD200, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD200, Rat |
| Clone | REA532 |
| Host Species | Recombinant Human |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD200 Antibody, anti-rat, FITC, REAfinity™. Clone REA532 recognizes the rat CD200 antigen, which is a transmembrane glycoprotein containing two extracellular immunoglobulin domains and lacks intracellular signaling motifs or docking sites for adapter signaling molecules. CD200, also known as MRC OX-2 antigen, is expressed on a variety of tissues, including the nervous system, activated T cells, B cells, dendritic cells in lymphatic follicles, cells of glomeruli and ovarian degenerating follicles, and vascular endothelium. It is also distributed at the epithelium-derived tissues such as the thymus, retinas, and hair follicles. CD200 interacts with CD200R, an immunoglobulin superfamily inhibitory receptor expressed primarily on myeloid/monocyte lineage cells, and has a suppressive effect on T cell-mediated immune response. | Additional information: Clone REA532 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | Cspmo2, MRCOX2, Mox2 |
| Gene, Accession # | Gene ID: 24560 |
| Catalog # | 130-108-125 |
| Price | $24 |
| Order / More Info | CD200, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Clark, M. J. et al. (1985) MRC OX-2 antigen: a lymphoid/neuronal membrane glycoprotein with a structure like a single immunoglobulin light chain. EMBO J. 4 (1): 113-118. | Ya-Fen, J. S. et al. (2010) Distribution and expression of CD200 in the rat respiratory system under normal and endotoxin-induced pathological conditions. J. Anat. 216 (3): 407-416. | Barclay, A. N. et al. (1986) Neuronal/lymphoid membrane glycoprotein MRC OX-2 is a member of the immunoglobulin superfamily with a light-chain-like structure. Biochem. Soc. Symp. 51: 149-157. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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