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Antigenic Specificity | CD45R (B220), Mouse |
Clone | REA755 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | VioGreen conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45R (B220) Antibody, anti-mouse, VioGreen™, REAfinity™. Clone REA755 recognizes the mouse CD45R (B220) antigen, a B lineage-specific surface molecule, which is expressed on B lymphocytes throughout their development from early pro-B stages onwards and is down-regulated upon terminal differentiation to plasma cells. Apart from B cells, CD45R is expressed on a small subset of dendritic cells (plasmacytoid dendritic cells). CD45R is absent in thymus but reported to be present on apoptotic thymocytes. Clone REA755 specifically recognizes the exon A-restricted isoform of mouse CD45. | Additional information: Clone REA755 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Ptprc, B220, CD45, loc, L-CA, Ly-5, Lyt-4, T200 |
Gene, Accession # | Gene ID: 19264 |
Catalog # | 130-110-715 |
Price | $510 |
Order / More Info | CD45R (B220), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Coffman, R. L. (1982) Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development. Immunol. Rev. 69: 5-23. | Katavic, V. et al. (2003) The surface antigen CD45R identifies a population of estrogen-regulated murine marrow cells that contain osteoclast precursors. Bone 32 (6): 581-590. |