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Antigenic Specificity | CD255 (TWEAK), Mouse |
Clone | REA1212 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD255 (TWEAK) Antibody, anti-mouse, APC, REAfinity™. Clone REA1212 recognizes the mouse CD255 also known as TWEAK which is a type II transmembrane member of the TNF superfamily with a molecular weight of 27 kDa. It is expressed on a variety of cell types and binds to the TWEAK receptor, Fn14. It functions as an inducer of apoptosis in some cell types, promotes angiogenesis and the proliferation of endothelial cells. Furthermore, it is implicated in the induction of inflammatory cytokines. | Additional information: Clone REA1212 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK |
Gene, Accession # | Gene ID: 21944 |
Catalog # | 130-123-375 |
Price | $91 |
Order / More Info | CD255 (TWEAK), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Schneider, P. et al. (1999) TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29 (6): 1785-1792. | Nakayama, M. et al. (2003) Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem. Biophys. Res. Commun. 306 (4): 819-825. | Lynch, C. N. et al. (1999) TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274: 8455-8459. |